Ingqungquthela Yomhlaba Wonke โ Ucwaningo Lwezokwelapha kanye Nomdlavuza (Juni 2023)
Irekhodi lenkulumo yethu eNgqungqutheleni Yomhlaba Wonke ye-Biomedical & Cancer Research ngoJuni 2023. Isihloko sithi โi-hypochlorous acid kanye ne-gauze yokuhlinzwa: inqubo yokwelapha amanxeba elula nephumelelayoโ.
Iseminari Ebonakalayo โ Ucwaningo Lwezokwelapha kanye Nomdlavuza (Feb 2023)
Iziguli ezithola ukwelashwa ngemisebe zivame ukugcina zinokulimala kwesikhumba njengoba imithamo ephezulu yemisebe ibangela umonakalo omkhulu ezicutshini nasesikhumbeni esinempilo. Lolu cwaningo luhlola ukusetshenziswa kwe-hypochlorous acid (HOCl) ekwelapheni ukulimala okukhulu kwemisebe kwesikhumba esingezansi kwejwabu leso, okubonisa ukuthi ukwelashwa ekhaya, okuqashwe umhlinzeki wezempilo, kungonga isikhathi nemali, futhi kuthuthukise ikhwalithi yokuphila kwesiguli.
Ucwaningo Lwecala โ Ukusetshenziswa kwe-hypochlorous acid ekwelapheni isilonda sezinyawo esinesifo sikashukela (Disemba 2022)
Lezi zifundo ezimbili zichaza ukwelashwa okuphumelelayo kwezilonda zezinyawo zesifo sikashukela (i-DFU) ezigulini ezimbili ezinesifo sikashukela sohlobo 1. I-HOCl iyasebenza ezifweni eziningi ezingamelani nemithi, ilwa ne-biofilm futhi ilawula ukuvuvukala, okuholela ekwelapheni. Le nqubo ingalandelwa ekhaya, isindisa isikhathi nemali yeziguli, futhi ithuthukise ukuthobela imithetho kanye nekhwalithi yokuphila.
Kuyini i-Biofilm?
Ukwakheka kwe-biofilm sekuyinkinga enkulu embonini yezempilo. Ucwaningo lunikeza ukuqonda kokuqonda izinqubo ezihilelekile ekubunjweni kwazo, kanye nezindlela zokulawula ukukhula nokusabalala kwazo. Ama-biofilm angakheka ezindaweni eziphilayo noma ezingaphili futhi avele ezindaweni zemvelo, zezimboni kanye nezibhedlela.
Ucwaningo Lwecala โ Ukusetshenziswa kwe-hypochlorous acid esilondeni esinomsebe weso elingezansi (Novemba 2021)
Ukwelashwa ngemisebe kuyisisekelo esibalulekile ekwelapheni izinhlobo eziningi zomdlavuza, njengoba kufakazelwa iqiniso lokuthi cishe ama-50% eziguli ezinomdlavuza azothola lolu hlobo lokwelashwa. Kuma-95% alaba bantu, ukwelashwa ngemisebe kubangela uhlobo oluthile lokulimala kwesikhumba njengoba imithamo ephezulu yemisebe ibangela umonakalo omkhulu ezicutshini nasesikhumbeni esinempilo. Ukuphathwa kokulimala ngenxa yemisebe e-ionizing kuyinselele, ngokulimala okusukela ebumnyameni obukhulu kuya ezilonda zesikhumba ezigcwele. Lokhu kungabangela ukukhathazeka okukhulu nokungakhululeki ezigulini. Lolu cwaningo luhlola ukusetshenziswa kwe-hypochlorous acid (HOCl) ekwelapheni ukulimala kwemisebe okukhulu kwesikhumba sejwabu elingezansi.
Ucwaningo Lwecala โ Ukusetshenziswa kwe-hypochlorous acid esilondeni esingezansi esingenwa yi-OXA-48 esingamelana nemithi eminingi i-Enterobacteriacea (Agasti 2021)
Lapha, sethula icala ngokutheleleka kwezilonda kwe-OXA-48 Klebsiella pneumoniae, igciwane le-Enterobacteriaceae MDR Gram-negative elikhiqiza i-carbapenemase elaphathwa ngempumelelo nge Trifectiv Plus hypochlorous acid gauze dressings egcinwe ngamabhandeji e-crepe. Le ndlela iphumelele ekuqedeni ukutheleleka kwe-OXA-48, futhi yasiza kakhulu ekulawuleni ukuvuvukala, okwavumela inxeba ukuthi liphilise ngokuphelele zingakapheli izinsuku ezingu-60.
Ukwelashwa Okuphumelelayo Kwezilonda Zezinyawo Ezinesifo Sikashukela
Iziguli eziningi ezinesifo sikashukela ziyalwa ne-Diabetic Foot Ulcers kodwa manje sekukhona ikhambi lokwelapha eliphumelelayo elibizwa ngokuthi Trifectiv Plus Wound & Burn Care, eliguqula indlela yokuphathwa kwe-DFU. Lokhu kwelashwa kuye kwavunyelwa yi-Diabetes SA.
Ucwaningo Lwecala โ Ukusetshenziswa kwe-hypochlorous acid esilondeni sokusha esinegciwane (Juni 2021)
Lapha sichaza isibonelo sesilonda sokusha esingapholi, esivuvukele, esinobukhulu obungaphezulu kuya kobuncane, esibonakala sihlotshaniswa ne-biofilm. Ukubhekisela okukhethekile ebuhlotsheni phakathi kwe-biofilm, ukuvuvukala kanye nokungapholi kwamanxeba okusha kuboniswe esifundweni esinikeziwe. Lesi sifundo siphinde sihlole ukusetshenziswa kwe-hypochlorous acid (HOCl) esilondeni sokusha esinegciwane.
Ucwaningo Lwesayensi lwe-MRSA (Novemba 2020)
Amalungiselelo e-HOCl akhiqizwa yi-Thoclor abonisa amandla okulwa ne-MRSA futhi aqede zonke izinhlobo ezinhlanu ze-MRSA zezokwelapha (MRSA 10, MRSA 42, MRSA 47, MRSA 52 kanye ne-MRSA 77) uma esetshenziswa ku-50% wezinga lokuqala kumthamo owodwa.
